PDF DatasheetMouse Heme oxygenase 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Heme oxygenase 1 based upon sequence from: Mouse
Host: QP9180 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Heme oxygenase 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9180.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met289
Amino Acid Sequence: MERPQPDSMP QDLSEALKEA TKEVHIQAEN AEFMKNFQKG QVSREGFKLV MASLYHIYTA LEEEIERNKQ NPVYAPLYFP EELHRRAALE QDMAFWYGPH WQEIIPCTPA TQHYVKRLHE VGRTHPELLV AHAYTRYLGD LSGGQVLKKI AQKAMALPSS GEGLAFFTFP NIDSPTKFKQ LYRARMNTLE MTPEVKHRVT EEAKTAFLLN IELFEELQVM LTEEHKDQSP SQMASLRQRP ASLVQDTAPA ETPRGKPQIS TSSSQTPLLQ WVLTLSFLLA TVAVGIYAM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Heme oxygenase 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Heme oxygenase 1 Protein General Information | |
|---|---|
| Alternate Names | |
| D8Wsu38e; HO-1; Hsp32; Hmox; HO1; Hemox | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Hmox1 |
| Entrez Gene ID | 15368 |
| Ensemble Gene ID | ENSMUSG00000005413 |
| RefSeq Protein Accession(s) | NP_034572.1 |
| RefSeq mRNA Accession(s) | NM_010442.2 |
| UniProt ID(s) | P14901 |
| UniGene ID(s) | Mm.276389 |
| COSMIC ID Link(s) | Hmox1 |
| KEGG Gene ID(s) | mmu:15368 |
| General Description of Recombinant Mouse Heme oxygenase 1 Protein. | |
| He oxygenase cleaves the he ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of he oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free he sensitizes cells to undergo apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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