PDF DatasheetHuman Cytokeratin 7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cytokeratin 7 based upon sequence from Human
Host: QP6283 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cytokeratin 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6283.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser2 – Asp469
Amino Acid Sequence: SIHFSSPVFT SRSAAFSGRG AQVRLSSARP GGLGSSSLYG LGASRPRVAV RSAYGGPVGA GIREVTINQS LLAPLRLDAD PSLQRVRQEE SEQIKTLNNK FASFIDKVRF LEQQNKLLET KWTLLQEQKS AKSSRLPDIF EAQIAGLRGQ LEALQVDGGR LEAELRSMQD VVEDFKNKYE DEINHRTAAE NEFVVLKKDV DAAYMSKVEL EAKVDALNDE INFLRTLNET ELTELQSQIS DTSVVLSMDN SRSLDLDGII AEVKAQYEEM AKCSRAEAEA WYQTKFETLQ AQAGKHGDDL RNTRNEISEM NRAIQRLQAE IDNIKNQRAK LEAAIAEAEE RGELALKDAR AKQEELEAAL QRGKQDMARQ LREYQELMSV KLALDIEIAT YRKLLEGEES RLAGDGVGAV NISVMNSTGG SSSGGGIGLT LGGTMGSNAL SFSSSAGPGL LKAYSIRTAS ASRRSARD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Cytokeratin 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cytokeratin 7 Protein General Information | |
|---|---|
| Alternate Names | |
| Cytokeratin 7, CK7, K2C7, K7, SCL | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | KRT7 |
| Entrez Gene ID | 3855 |
| Ensemble Gene ID | ENSG00000135480 |
| RefSeq Protein Accession(s) | NP_005547.3 |
| RefSeq mRNA Accession(s) | NM_005556.3 |
| UniProt ID(s) | P08729 |
| UniGene ID(s) | Hs.411501 |
| HGNC ID(s) | HGNC:6445 |
| COSMIC ID Link(s) | KRT7 |
| KEGG Gene ID(s) | hsa:3855 |
| PharmGKB ID(s) | PA30233 |
| General Description of Recombinant Human Cytokeratin 7 Protein. | |
| Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
![Analysis of Mass Spec data (dashed-line) of fractions stained with Cytokeratin 7 MS-QAVA™ monoclonal antibody [Clone: KRT7/903] (solid-line), reveals that less than 7.5% of signal is attributable to non-specific binding of anti-Cytokeratin 7 [Clone KRT7/903] to targets other than KRT7 protein. Even frequently cited antibodies have much greater non-specific interactions, averaging over 30%. Data in image is from analysis in A431, RT4 and MCF7 cells.](https://cdn-enquirebio.pressidium.com/wp-content/uploads/2017/10/enQuire-Bio-3855-MSM3-P1-anti-Cytokeratin-7-antibody-150x150.png)
![Analysis of Mass Spec data (dashed-line) of fractions stained with Cytokeratin 7 MS-QAVA™ monoclonal antibody [Clone: KRT7/1499R] (solid-line), reveals that less than 13.6% of signal is attributable to non-specific binding of anti-Cytokeratin 7 [Clone KRT7/1499R] to targets other than KRT7 protein. Even frequently cited antibodies have much greater non-specific interactions, averaging over 30%. Data in image is from analysis in A431, RT4 and MCF7 cells.](https://cdn-enquirebio.pressidium.com/wp-content/uploads/2017/10/enQuire-Bio-3855-RBM9-P0-anti-Cytokeratin-7-antibody-150x150.png)
![Analysis of Mass Spec data (dashed-line) of fractions stained with Cytokeratin 7 MS-QAVA™ monoclonal antibody [Clone: KRT7/760 + KRT7/903] (solid-line), reveals that less than 0.3% of signal is attributable to non-specific binding of anti-Cytokeratin 7 [Clone KRT7/760 + KRT7/903] to targets other than KRT7 protein. Even frequently cited antibodies have much greater non-specific interactions, averaging over 30%. Data in image is from analysis in Jurkat, U202 and HeLa cells.](https://cdn-enquirebio.pressidium.com/wp-content/uploads/2017/10/enQuire-Bio-3855-MSM5-P1-anti-Cytokeratin-7-antibody-150x150.png)
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