PDF DatasheetHuman LY-96 / ESOP-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant LY-96 / ESOP-1 based upon sequence from Human
Host: QP6326 protein expressed in E. coli.
Tag: His-GST-Myc
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) LY-96 / ESOP-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6326.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu17 – Asn160
Amino Acid Sequence: EAQKQYWVCN SSDASISYTY CDKMQYPISI NVNPCIELKR SKGLLHIFYI PRRDLKQLYF NLYITVNTMN LPKRKEVICR GSDDDYSFCR ALKGETVNTT ISFSFKGIKF SKGKYKCVVE AISGSPEEML FCLEFVILHQ PNSN
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human LY-96 / ESOP-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human LY-96 / ESOP-1 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LY96 |
| Entrez Gene ID | 23643 |
| Ensemble Gene ID | ENSG00000154589 |
| RefSeq Protein Accession(s) | NP_001182726.1 |
| RefSeq mRNA Accession(s) | NM_001195797.1, NM_015364.4 |
| UniProt ID(s) | Q9Y6Y9 |
| UniGene ID(s) | Hs.726603 |
| HGNC ID(s) | HGNC:17156 |
| COSMIC ID Link(s) | LY96 |
| KEGG Gene ID(s) | hsa:23643 |
| PharmGKB ID(s) | PA134924906 |
| General Description of Recombinant Human LY-96 / ESOP-1 Protein. | |
| Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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