Mouse LY-96 / ESOP-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant LY-96 / ESOP-1 based upon sequence from Mouse
Host: QP6327 protein expressed in E.coli, Mammal..
Tag: Flag
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) LY-96 / ESOP-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6327.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu19 – Asn160
Amino Acid Sequence: EKQQWFCNSS DAIISYSYCD HLKFPISISS EPCIRLRGTN GFVHVEFIPR GNLKYLYFNL FISVNSIELP KRKEVLCHGH DDDYSFCRAL KGETVNTSIP FSFEGILFPK GHYRCVAEAI AGDTEEKLFC LNFTIIHRRD VN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse LY-96 / ESOP-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Mouse LY-96 / ESOP-1 Protein General Information | |
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Alternate Names | |
LY-96, ESOP-1, MD-2, ESOP-1, MD2 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | LY96 |
Entrez Gene ID | 17087 |
Ensemble Gene ID | ENSMUSG00000025779 |
RefSeq Protein Accession(s) | NP_001153183.1 |
RefSeq mRNA Accession(s) | NM_001159711.1, NM_016923.2 |
UniProt ID(s) | Q9JHF9 |
UniGene ID(s) | Mm.116844 |
COSMIC ID Link(s) | LY96 |
KEGG Gene ID(s) | mmu:17087 |
General Description of Recombinant Mouse LY-96 / ESOP-1 Protein. | |
Binds bacterial lipopolysaccharide (LPS) (PubMed:22532668). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10725698). |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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