PDF DatasheetHuman Major Vault Protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Major Vault Protein based upon sequence from Human
Host: QP6397 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Major Vault Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6397.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Arg893
Amino Acid Sequence: ATEEFIIRIP PYHYIHVLDQ NSNVSRVEVG PKTYIRQDNE RVLFAPMRMV TVPPRHYCTV ANPVSRDAQG LVLFDVTGQV RLRHADLEIR LAQDPFPLYP GEVLEKDITP LQVVLPNTAL HLKALLDFED KDGDKVVAGD EWLFEGPGTY IPRKEVEVVE IIQATIIRQN QALRLRARKE CWDRDGKERV TGEEWLVTTV GAYLPAVFEE VLDLVDAVIL TEKTALHLRA RRNFRDFRGV SRRTGEEWLV TVQDTEAHVP DVHEEVLGVV PITTLGPHNY CVILDPVGPD GKNQLGQKRV VKGEKSFFLQ PGEQLEQGIQ DVYVLSEQQG LLLRALQPLE EGEDEEKVSH QAGDHWLIRG PLEYVPSAKV EVVEERQAIP LDENEGIYVQ DVKTGKVRAV IGSTYMLTQD EVLWEKELPP GVEELLNKGQ DPLADRGEKD TAKSLQPLAP RNKTRVVSYR VPHNAAVQVY DYREKRARVV FGPELVSLGP EEQFTVLSLS AGRPKRPHAR RALCLLLGPD FFTDVITIET ADHARLQLQL AYNWHFEVND RKDPQETAKL FSVPDFVGDA CKAIASRVRG AVASVTFDDF HKNSARIIRT AVFGFETSEA KGPDGMALPR PRDQAVFPQN GLVVSSVDVQ SVEPVDQRTR DALQRSVQLA IEITTNSQEA AAKHEAQRLE QEARGRLERQ KILDQSEAEK ARKELLELEA LSMAVESTGT AKAEAESRAE AARIEGEGSV LQAKLKAQAL AIETEAELQR VQKVRELELV YARAQLELEV SKAQQLAEVE VKKFKQMTEA IGPSTIRDLA VAGPEMQVKL LQSLGLKSTL ITDGSTPINL FNTAFGLLGM GPEGQPLGRR VASGPSPGEG ISPQSAQAPQ APGDNHVVPV LR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Major Vault Protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Major Vault Protein Protein General Information | |
|---|---|
| Alternate Names | |
| Major Vault Protein, LRP, VAULT1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MVP |
| Entrez Gene ID | 9961 |
| Ensemble Gene ID | ENSG00000013364 |
| RefSeq Protein Accession(s) | NP_001280133.1 |
| RefSeq mRNA Accession(s) | NM_001293204.1, NM_001293205.1, NM_005115.4, NM_017458.3 |
| UniProt ID(s) | Q14764 |
| UniGene ID(s) | Hs.632177 |
| HGNC ID(s) | HGNC:7531 |
| COSMIC ID Link(s) | MVP |
| KEGG Gene ID(s) | hsa:9961 |
| PharmGKB ID(s) | PA31332 |
| General Description of Recombinant Human Major Vault Protein Protein. | |
| Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-Cytoplasmic domain transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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