PDF DatasheetMouse NKX2.2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant NKX2.2 based upon sequence from Mouse
Host: QP6423 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) NKX2.2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6423.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Trp273
Amino Acid Sequence: MSLTNTKTGF SVKDILDLPD TNDEDGSVAE GPEEESEGPE PAKRAGPLGQ GALDAVQSLP LKSPFYDSSD NPYTRWLAST EGLQYSLHGL AASAPPQDSS SKSPEPSADE SPDNDKETQG GGGDAGKKRK RRVLFSKAQT YELERRFRQQ RYLSAPEREH LASLIRLTPT QVKIWFQNHR YKMKRARAEK GMEVTPLPSP RRVAVPVLVR DGKPCHALKA QDLAAATFQA GIPFSAYSAQ SLQHMQYNAQ YSSASTPQYP TAHPLVQAQQ WTW
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse NKX2.2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse NKX2.2 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Nkx2-2 |
| Entrez Gene ID | 18088 |
| Ensemble Gene ID | ENSMUSG00000027434 |
| RefSeq Protein Accession(s) | NP_035049.1 |
| RefSeq mRNA Accession(s) | NM_010919.2, XM_006498898.2, XM_006498899.2, XM_006498900.3, XM_011239349.2 |
| UniProt ID(s) | P42586 |
| UniGene ID(s) | Mm.330639 |
| COSMIC ID Link(s) | Nkx2-2 |
| KEGG Gene ID(s) | mmu:18088 |
| General Description of Recombinant Mouse NKX2.2 Protein. | |
| Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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