PDF DatasheetHuman tPA / PLAT Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant tPA / PLAT based upon sequence from Human
Host: QP6501 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) tPA / PLAT, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6501.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser36 – Ile556
Amino Acid Sequence: SYQVICRDEK TQMIYQQHQS WLRPVLRSNR VEYCWCNSGR AQCHSVPVKS CSEPRCFNGG TCQQALYFSD FVCQCPEGFA GKCCEIDTRA TCYEDQGISY RGTWSTAESG AECTNWNSSA LAQKPYSGRR PDAIRLGLGN HNYCRNPDRD SKPWCYVFKA GKYSSEFCST PACSEGNSDC YFGNGSAYRG THSLTESGAS CLPWNSMILI GKVYTAQNPS AQALGLGKHN YCRNPDGDAK PWCHVLKNRR LTWEYCDVPS CSTCGLRQYS QPQFRIKGGL FADIASHPWQ AAIFAKHRRS PGERFLCGGI LISSCWILSA AHCFQERFPP HHLTVILGRT YRVVPGEEEQ KFEVEKYIVH KEFDDDTYDN DIALLQLKSD SSRCAQESSV VRTVCLPPAD LQLPDWTECE LSGYGKHEAL SPFYSERLKE AHVRLYPSSR CTSQHLLNRT VTDNMLCAGD TRSGGPQANL HDACQGDSGG PLVCLNDGRM TLVGIISWGL GCGQKDVPGV YTKVTNYLDW I
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human tPA / PLAT Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human tPA / PLAT Protein (36-556aa) General Information | |
|---|---|
| Alternate Names | |
| tPA, PLAT, AU020998, AW212668, tPA, D8Ertd2e | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PLAT |
| Entrez Gene ID | 5327 |
| Ensemble Gene ID | ENSG00000104368 |
| RefSeq Protein Accession(s) | NP_000921.1 |
| RefSeq mRNA Accession(s) | NM_000930.4, NM_001319189.1, NM_033011.3 |
| UniProt ID(s) | P00750 |
| UniGene ID(s) | Hs.491582 |
| HGNC ID(s) | HGNC:9051 |
| COSMIC ID Link(s) | PLAT |
| KEGG Gene ID(s) | hsa:5327 |
| PharmGKB ID(s) | PA33381 |
| General Description of Recombinant Human tPA / PLAT Protein (36-556aa). | |
| Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue rodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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