PDF DatasheetHuman tPA / PLAT Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant tPA / PLAT based upon sequence from Human
Host: QP6502 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) tPA / PLAT, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6502.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ile311 – Ile556
Amino Acid Sequence: IKGGLFADIA SHPWQAAIFA KHRRSPGERF LCGGILISSC WILSAAHCFQ ERFPPHHLTV ILGRTYRVVP GEEEQKFEVE KYIVHKEFDD DTYDNDIALL QLKSDSSRCA QESSVVRTVC LPPADLQLPD WTECELSGYG KHEALSPFYS ERLKEAHVRL YPSSRCTSQH LLNRTVTDNM LCAGDTRSGG PQANLHDACQ GDSGGPLVCL NDGRMTLVGI ISWGLGCGQK DVPGVYTKVT NYLDWI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human tPA / PLAT Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human tPA / PLAT Protein (311-556aa) General Information | |
|---|---|
| Alternate Names | |
| tPA, PLAT, AU020998, AW212668, tPA, D8Ertd2e | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PLAT |
| Entrez Gene ID | 5327 |
| Ensemble Gene ID | ENSG00000104368 |
| RefSeq Protein Accession(s) | NP_000921.1 |
| RefSeq mRNA Accession(s) | NM_000930.4, NM_001319189.1, NM_033011.3 |
| UniProt ID(s) | P00750 |
| UniGene ID(s) | Hs.491582 |
| HGNC ID(s) | HGNC:9051 |
| COSMIC ID Link(s) | PLAT |
| KEGG Gene ID(s) | hsa:5327 |
| PharmGKB ID(s) | PA33381 |
| General Description of Recombinant Human tPA / PLAT Protein (311-556aa). | |
| Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue rodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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