PDF DatasheetMouse AIMP1 / EMAP2 / SCYE1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant AIMP1 / EMAP2 / SCYE1 based upon sequence from Mouse
Host: QP6654 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) AIMP1 / EMAP2 / SCYE1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6654.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Lys310
Amino Acid Sequence: ATNDAVLKRL EQKGAEADQI IEYLKQQVAL LKEKAILQAT MREEKKLRVE NAKLKKEIEE LKQELILAEI HNGVEQVRVR LSTPLQTNCT ASESVVQSPS VATTASPATK EQIKAGEEKK VKEKTEKKGE KKEKQQSAAA STDSKPIDAS RLDLRIGCIV TAKKHPDADS LYVEEVDVGE AAPRTVVSGL VNHVPLEQMQ NRMVVLLCNL KPAKMRGVLS QAMVMCASSP EKVEILAPPN GSVPGDRITF DAFPGEPDKE LNPKKKIWEQ IQPDLHTNAE CVATYKGAPF EVKGKGVCRA QTMANSGIK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse AIMP1 / EMAP2 / SCYE1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse AIMP1 / EMAP2 / SCYE1 Protein General Information | |
|---|---|
| Alternate Names | |
| AIMP1, EMAP2, SCYE1, SCYE1, EMAP2, EMAPII, HLD3, p43 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Aimp1 |
| UniProt ID(s) | P31230 |
| UniGene ID(s) | Mm.235137 |
| COSMIC ID Link(s) | Aimp1 |
| General Description of Recombinant Mouse AIMP1 / EMAP2 / SCYE1 Protein. | |
| Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of Cytoplasmic domain arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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