PDF DatasheetMouse TIMP-1 / TIMP1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TIMP-1 / TIMP1 based upon sequence from Mouse
Host: QP6795 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) TIMP-1 / TIMP1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6795.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Cys25 – Arg205
Amino Acid Sequence: CSCAPPHPQT AFCNSDLVIR AKFMGSPEIN ETTLYQRYKI KMTKMLKGFK AVGNAADIRY AYTPVMESLC GYAHKSQNRS EEFLITGRLR NGNLHISACS FLVPWRTLSP AQQRAFSKTY SAGCGVCTVF PCLSIPCKLE SDTHCLWTDQ VLVGSEDYQS RHFACLPRNP GLCTWRSLGA R
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse TIMP-1 / TIMP1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse TIMP-1 / TIMP1 Protein General Information | |
|---|---|
| Alternate Names | |
| TIMP-1, TIMP1, EPO, TIMP-1, EPA, HCI, CLGI, TIMP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Timp1 |
| Entrez Gene ID | 21857 |
| Ensemble Gene ID | ENSMUSG00000001131 |
| RefSeq Protein Accession(s) | NP_001037849.1 |
| RefSeq mRNA Accession(s) | NM_001044384.1, NM_011593.2 |
| UniProt ID(s) | P12032 |
| UniGene ID(s) | Mm.8245 |
| COSMIC ID Link(s) | Timp1 |
| KEGG Gene ID(s) | mmu:21857 |
| General Description of Recombinant Mouse TIMP-1 / TIMP1 Protein. | |
| Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates th by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 . Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.1 Publication | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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