PDF DatasheetHuman Tyrosinase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tyrosinase based upon sequence from Human
Host: QP6860 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tyrosinase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6860.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: His19 – Val377
Amino Acid Sequence: HFPRACVSSK NLMEKECCPP WSGDRSPCGQ LSGRGSCQNI LLSNAPLGPQ FPFTGVDDRE SWPSVFYNRT CQCSGNFMGF NCGNCKFGFW GPNCTERRLL VRRNIFDLSA PEKDKFFAYL TLAKHTISSD YVIPIGTYGQ MKNGSTPMFN DINIYDLFVW MHYYVSMDAL LGGSEIWRDI DFAHEAPAFL PWHRLFLLRW EQEIQKLTGD ENFTIPYWDW RDAEKCDICT DEYMGGQHPT NPNLLSPASF FSSWQIVCSR LEEYNSHQSL CNGTPEGPLR RNPGNHDKSR TPRLPSSADV EFCLSLTQYE SGSMDKAANF SFRNTLEGFA SPLTGIADAS QSSMHNALHI YMNGTMSQV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Tyrosinase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Tyrosinase Protein General Information | |
|---|---|
| Alternate Names | |
| Tyrosinase, OCA1, OCA1A, ATN, OCAIA, SHEP3, CMM8 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TYR |
| Entrez Gene ID | 7299 |
| Ensemble Gene ID | ENSG00000077498 |
| RefSeq Protein Accession(s) | NP_000363.1 |
| RefSeq mRNA Accession(s) | NM_000372.4 |
| UniProt ID(s) | P14679 |
| UniGene ID(s) | Hs.503555 |
| HGNC ID(s) | HGNC:12442 |
| COSMIC ID Link(s) | TYR |
| KEGG Gene ID(s) | hsa:7299 |
| PharmGKB ID(s) | PA37095 |
| General Description of Recombinant Human Tyrosinase Protein. | |
| This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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