PDF DatasheetM. tuberculosis Ag85B Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ag85B based upon sequence from: M. tuberculosis
Host: QP7004 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) Ag85B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7004.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Phe41 – Gly325
Amino Acid Sequence: FSRPGLPVEY LQVPSPSMGR DIKVQFQSGG NNSPAVYLLD GLRAQDDYNG WDINTPAFEW YYQSGLSIVM PVGGQSSFYS DWYSPACGKA GCQTYKWETF LTSELPQWLS ANRAVKPTGS AAIGLSMAGS SAMILAAYHP QQFIYAGSLS ALLDPSQGMG PSLIGLAMGD AGGYKAADMW GPSSDPAWER NDPTQQIPKL VANNTRLWVY CGNGTPNELG GANIPAEFLE NFVRSSNLKF QDAYNAAGGH NAVFNFPPNG THSWEYWGAQ LNAMKGDLQS SLGAG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of M. tuberculosis Ag85B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant M. tuberculosis Ag85B Protein General Information | |
|---|---|
| Alternate Names | |
| , Diacylglycerol acyltransferase/mycolyltransferase Ag8 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | fbpB |
| RefSeq Protein Accession(s) | WP_003409456.1 |
| RefSeq mRNA Accession(s) | NZ_KK341227.1 |
| UniProt ID(s) | P9WQP0 |
| KEGG Gene ID(s) | mtc:MT1934 |
| General Description of Recombinant M. tuberculosis Ag85B Protein. | |
| The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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