PDF DatasheetCytomegalovirus Viral interleukin-10 homolog Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Viral interleukin-10 homolog based upon sequence from: Cytomegalovirus
Host: QP7080 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) Viral interleukin-10 homolog, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7080.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser20 – Lys175
Amino Acid Sequence: SEEAKPATTT IKNTKPQCRP EDYATRLQDL RVTFHRVKPT LQREDDYSVW LDGTVVKGCW GCSVMDWLLR RYLEIVFPAG DHVYPGLKTE LHSMRSTLES IYKDMRQCPL LGCGDKSVIS RLSQEAERKS DNGTRKGLSE LDTLFSRLEE YLHSRK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Cytomegalovirus Viral interleukin-10 homolog Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Cytomegalovirus Viral interleukin-10 homolog Protein (20-175aa) General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | UL111A |
| UniProt ID(s) | P17150 |
| General Description of Recombinant Cytomegalovirus Viral interleukin-10 homolog Protein (20-175aa). | |
| Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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