PDF DatasheetCytomegalovirus Viral interleukin-10 homolog Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Viral interleukin-10 homolog based upon sequence from: Cytomegalovirus
Host: QP7461 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5) Viral interleukin-10 homolog, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7461.
Bioactivity Data: Untested
Full Length? Full Length of Mature Protein
Expression Region: Ala26 – Lys176
Amino Acid Sequence: ATTTTIKNTK PQCRPEDYAT RLQDLRVTFH RVKPTLQRED DYSVWLDGTV VKGCWGCSVM DWLLRRYLEI VFPAGDHVYP GLKTELHSMR STLESIYkDa MRQCPLLGCG DKSVISRLSQ EAERKSDNGT RKGLSELDTL FSRLEEYLHS RK
Purity: Greater than 95.8% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Cytomegalovirus Viral interleukin-10 homolog Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Cytomegalovirus Viral interleukin-10 homolog Protein (26-176aa) General Information | |
|---|---|
| Alternate Names | |
| HHV5wtgp098 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | UL111A |
| Entrez Gene ID | 3077506 |
| RefSeq Protein Accession(s) | YP_081552.1 |
| RefSeq mRNA Accession(s) | NC_006273.2 |
| UniProt ID(s) | F5HC71 |
| KEGG Gene ID(s) | vg:3077506 |
| General Description of Recombinant Cytomegalovirus Viral interleukin-10 homolog Protein (26-176aa). | |
| Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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