PDF DatasheetHuman Regulatory protein E2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Regulatory protein E2 based upon sequence from: Human
Host: QP7368 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Regulatory protein E2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7368.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met365
Amino Acid Sequence: MQTPKETLSE RLSCVQDKII DHYENDSKDI DSQIQYWQLI RWENAIFFAA REHGIQTLNH QVVPAYNISK SKAHKAIELQ MALQGLAQSA YKTEDWTLQD TCEELWNTEP THCFKKGGQT VQVYFDGNKD NCMTYVAWDS VYYMTDAGTW DKTATCVSHR GLYYVKEGYN TFYIEFKSEC EKYGNTGTWE VHFGNNVIDC NDSMCSTSDD TVSATQLVKQ LQHTPSPYSS TVSVGTAKTY GQTSAATRPG HCGLAEKQHC GPVNPLLGAA TPTGNNKRRK LCSGNTTPII HLKGDRNSLK CLRYRLRKHS DHYRDISSTW HWTGAGNEKT GILTVTYHSE TQRTKFLNTV AIPDSVQILV GYMTM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Regulatory protein E2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Regulatory protein E2 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | E2 |
| UniProt ID(s) | P06790 |
| General Description of Recombinant Human Regulatory protein E2 Protein. | |
| E2 regulates viral transcription and DNA replication. It binds to the E2RE response elent (5′-ACCNNNNNNGGT-3′) present in multiple copies in the regulatory region. It can either activate or repress transcription depending on E2RE’s position with regards to proximal promoter elents. Repression occurs by sterically hindering the assbly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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