PDF DatasheetRABV Glycoprotein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glycoprotein based upon sequence from: RABV
Host: QP7425 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Rabies virus (strain PM) (RABV) Glycoprotein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7425.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Lys20 – Tyr459
Amino Acid Sequence: KFPIYTIPDK LGPWSPIDIH HLSCPNNLVV EDEGCTNLSG FSYMELKVGY ISAIKVNGFT CTGVVTEAET YTNFVGYVTT TFKRKHFRPT PDACRAAYNW KMAGDPRYEE SLHNPYPDYH WLRTVKTTKE SLVIISPSVA DLDPYDKSLH SRVFPSGKCS GITISSTYCS TNHDYTIWMP ENPRLGTSCD IFTNSRGKRA SKGGKTCGFV DERGLYKSLK GACKLKLCGV LGLRLMDGTW VAMQTSDETK WCPPDQLVNL HDFRSDEIEH LVVEELVKKR EECLDALESI MATKSVSFRR LSHLRKLVPG FGKAYTIFNK TLMEADAHYK SVRTWNEIIP SKGCLRVGGR CHPHVNGVFF NGIILGPDGH VLIPEMQSSL LQQHMELLES SVIPLMHPLA DPSTVFKDGD EAEDFVEVHL PDVHKQISGV DLGLPSWGKY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of RABV Glycoprotein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant RABV Glycoprotein Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | G |
| UniProt ID(s) | A3RM22 |
| General Description of Recombinant RABV Glycoprotein Protein. | |
| Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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