PDF DatasheetRABV Glycoprotein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glycoprotein based upon sequence from: RABV
Host: QP9556 protein expressed in Baculovirus, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Rabies virus (strain HEP-Flury) (RABV) Glycoprotein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9556.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys20 – Tyr459
Amino Acid Sequence: KFPIYTIPDK LGPWSPIDLH HLSCPNNLVV EDEGCTNLSG FSYMELKVGY ISAIKVNGFT CTGVVTEAET YTNFVGYVTT TFKRKHFRPT PDACRAAYNW KMAGDPRYEE SLHNPYPDYH WLRTVKTTKE SLVIISPSVT DLDPYDKSLH SRVFPGGNCS GITVSSTYCS TNHDYTIWMP ENLRLGTSCD IFTHSRGKRA SKGDKTCGFV DERGLYKSLK GACKLKLCGV LGLRLMDGTW VAMQTSDETK WCPPGQLVNL HDFRSDEIEH LVEEELVKKR EECLDALESI MTTKSVSFRR LSHLRKLVPG FGKAYTIFNK TLMEADAHYK SVQTWNEIIP SKGCLRVGER CHPHVNGVFF NGIILGSDGH VLIPEMQSSL LQQHMELLES SVIPLMHPLA DPSTVFKDGD EVEDFVEVHL PDVHKQVSGV DLGLPKWGKY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of RABV Glycoprotein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant RABV Glycoprotein Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | G |
| UniProt ID(s) | P19462 |
| General Description of Recombinant RABV Glycoprotein Protein. | |
| Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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