Human Mucosal addressin cell adhesion molecule 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Mucosal addressin cell adhesion molecule 1 based upon sequence from: Human
Host: QP7559 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Mucosal addressin cell adhesion molecule 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7559.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln19 – Gln317
Amino Acid Sequence: QSLQVKPLQV EPPEPVVAVA LGASRQLTCR LACADRGASV QWRGLDTSLG AVQSDTGRSV LTVRNASLSA AGTRVCVGSC GGRTFQHTVQ LLVYAFPDQL TVSPAALVPG DPEVACTAHK VTPVDPNALS FSLLVGGQEL EGAQALGPEV QEEEEEPQGD EDVLFRVTER WRLPPLGTPV PPALYCQATM RLPGLELSHR QAIPVLHSPT SPEPPDTTSP ESPDTTSPES PDTTSQEPPD TTSPEPPDKT SPEPAPQQGS THTPRSPGST RTRRPEISQA GPTQGEVIPT GSSKPAGDQ
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Mucosal addressin cell adhesion molecule 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Mucosal addressin cell adhesion molecule 1 Protein General Information | |
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Alternate Names | |
MACAM1 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | Madcam1 |
Entrez Gene ID | 8174 |
Ensemble Gene ID | ENSG00000099866 |
RefSeq Protein Accession(s) | NP_570116.2 |
RefSeq mRNA Accession(s) | NM_130760.2, NM_130762.2 |
UniProt ID(s) | Q13477 |
UniGene ID(s) | Hs.102598 |
HGNC ID(s) | HGNC:6765 |
COSMIC ID Link(s) | Madcam1 |
KEGG Gene ID(s) | hsa:8174 |
PharmGKB ID(s) | PA30522 |
General Description of Recombinant Human Mucosal addressin cell adhesion molecule 1 Protein. | |
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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