PDF DatasheetMouse Mucosal addressin cell adhesion molecule 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Mucosal addressin cell adhesion molecule 1 based upon sequence from: Mouse
Host: QP7689 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Mucosal addressin cell adhesion molecule 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7689.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln22 – Ser364
Amino Acid Sequence: QSFQVNPPES EVAVAMGTSL QITCSMSCDE GVARVHWRGL DTSLGSVQTL PGSSILSVRG MLSDTGTPVC VGSCGSRSFQ HSVKILVYAF PDQLVVSPEF LVPGQDQVVS CTAHNIWPAD PNSLSFALLL GEQRLEGAQA LEPEQEEEIQ EAEGTPLFRM TQRWRLPSLG TPAPPALHCQ VTMQLPKLVL THRKEIPVLQ SQTSPKPPNT TSAEPYILTS SSTAEAVSTG LNITTLPSAP PYPKLSPRTL SSEGPCRPKI HQDLEAGWEL LCEASCGPGV TVRWTLAPGD LATYHKREAG AQAWLSVLPP GPMVEGWFQC RQDPGGEVTN LYVPGQVTPN SSS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Mucosal addressin cell adhesion molecule 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Mucosal addressin cell adhesion molecule 1 Protein General Information | |
|---|---|
| Alternate Names | |
| AV211525 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Madcam1 |
| Entrez Gene ID | 17123 |
| Ensemble Gene ID | ENSMUSG00000020310 |
| RefSeq Protein Accession(s) | XP_006513356.1 |
| RefSeq mRNA Accession(s) | XM_006513293.3 |
| UniProt ID(s) | Q61826 |
| UniGene ID(s) | Mm.391556 |
| COSMIC ID Link(s) | Madcam1 |
| General Description of Recombinant Mouse Mucosal addressin cell adhesion molecule 1 Protein. | |
| Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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