Mouse GRK2 / ADRBK1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GRK2 / ADRBK1 based upon sequence from: Mouse
Host: QP8014 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) GRK2 / ADRBK1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8014.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu689
Amino Acid Sequence: MADLEAVLAD VSYLMAMEKS KATPAARASK KILLPEPSIR SVMQKYLEDR GEVTFEKIFS QKLGYLLFRD FCLNHLEEAK PLVEFYEEIK KYEKLETEEE RVVRSREIFD SYIMKELLAC SHPFSKNATE HVQGHLVKKQ VPPDLFQPYI EEICQNLRGD VFQKFIESDK FTRFCQWKNV ELNIHLTMND FSVHRIIGRG GFGEVYGCRK ADTGKMYAMK CLDKKRIKMK QGETLALNER IMLSLVSTGD CPFIVCMSYA FHTPDKLSFI LDLMNGGDLH YHLSQHGVFS EADMRFYAAE IILGLEHMHN RFVVYRDLKP ANILLDEHGH VRISDLGLAC DFSKKRPHAS VGTHGYMAPE VLQKGVAYDS SADWFSLGCM LFKLLRGHSP FRQHKTKDKH EIDRMTLTMA VELPDSFSPE LRSLLEGLLQ RDVNRRLGCL GRGAQEVKES PFFRSLDWQM VFLQKYPPPL IPPRGEVNAA DAFDIGSFDE EDTKGIKLLD SDQELYRNFP LTISERWQQE VAETVFDTIN AETDRLEARK KAKNKQLGHE EDYALGKDCI VHGYMSKMGN PFLTQWQRRY FYLFPNRLEW RGEGEAPQSL LTMEEIQSVE ETQIKERKCL LLKIRGGKQF VLQCDSDPEL VQWKKELRDA YREAQQLVQR VPKMKNKPRS PVVELSKVPL IQRGSANGL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse GRK2 / ADRBK1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Mouse GRK2 / ADRBK1 Protein General Information | |
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Curated Database and Bioinformatic Data | |
Gene Symbol | Adrbk1 |
Entrez Gene ID | 110355 |
Ensemble Gene ID | ENSMUSG00000024858 |
RefSeq Protein Accession(s) | NP_001277747.1 |
RefSeq mRNA Accession(s) | NM_001290818.1 |
UniProt ID(s) | Q99MK8 |
UniGene ID(s) | Mm.254144 |
COSMIC ID Link(s) | Adrbk1 |
KEGG Gene ID(s) | mmu:110355 |
General Description of Recombinant Mouse GRK2 / ADRBK1 Protein. | |
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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