PDF DatasheetHuman Oncostatin M / OSM Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Oncostatin M / OSM based upon sequence from: Human
Host: QP8301 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Oncostatin M / OSM, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8301.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala26 – Arg221
Amino Acid Sequence: AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Oncostatin M / OSM Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Oncostatin M / OSM Protein (26-221aa) General Information | |
|---|---|
| Alternate Names | |
| Oncostatin M; OSM; OncoM | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | OSM |
| Entrez Gene ID | 5008 |
| Ensemble Gene ID | ENSG00000099985 |
| RefSeq Protein Accession(s) | NP_001306037.1 |
| RefSeq mRNA Accession(s) | NM_001319108.1, NM_020530.5 |
| UniProt ID(s) | P13725 |
| UniGene ID(s) | Hs.248156 |
| HGNC ID(s) | HGNC:8506 |
| COSMIC ID Link(s) | OSM |
| KEGG Gene ID(s) | hsa:5008 |
| PharmGKB ID(s) | PA32836 |
| General Description of Recombinant Human Oncostatin M / OSM Protein (26-221aa). | |
| Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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