PDF DatasheetHuman Fibroblast growth factor 19 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Fibroblast growth factor 19 based upon sequence from: Human
Host: QP8543 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Fibroblast growth factor 19, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8543.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Pro32 – Lys216
Amino Acid Sequence: PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Fibroblast growth factor 19 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Fibroblast growth factor 19 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF19 |
| Entrez Gene ID | 9965 |
| Ensemble Gene ID | ENSG00000162344 |
| RefSeq Protein Accession(s) | NP_005108.1 |
| RefSeq mRNA Accession(s) | NM_005117.2 |
| UniProt ID(s) | O95750 |
| UniGene ID(s) | Hs.249200 |
| HGNC ID(s) | HGNC:3675 |
| COSMIC ID Link(s) | FGF19 |
| KEGG Gene ID(s) | hsa:9965 |
| PharmGKB ID(s) | PA28114 |
| General Description of Recombinant Human Fibroblast growth factor 19 Protein. | |
| Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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