PDF DatasheetHuman IGF1 Isoform 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IGF1 Isoform 2 based upon sequence from: Human
Host: QP8549 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IGF1 Isoform 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8549.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly49 – Ala118
Amino Acid Sequence: GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IGF1 Isoform 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IGF1 Isoform 2 Protein General Information | |
|---|---|
| Alternate Names | |
| IGF1; IGF-I; IGF-I; MGF; IGFI | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IGF1 |
| Entrez Gene ID | 3479 |
| Ensemble Gene ID | ENSG00000017427 |
| RefSeq Protein Accession(s) | NP_000609.1 |
| RefSeq mRNA Accession(s) | NM_000618.4, NM_001111284.1, NM_001111285.2 |
| UniProt ID(s) | P05019 |
| UniGene ID(s) | Hs.160562 |
| HGNC ID(s) | HGNC:5464 |
| COSMIC ID Link(s) | IGF1 |
| KEGG Gene ID(s) | hsa:3479 |
| PharmGKB ID(s) | PA29697 |
| General Description of Recombinant Human IGF1 Isoform 2 Protein. | |
| The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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