PDF DatasheetHuman NAP-2 / PPBP / CXCL7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant NAP-2 / PPBP / CXCL7 based upon sequence from: Human
Host: QP8641 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) NAP-2 / PPBP / CXCL7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8641.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala59 – Glu125
Amino Acid Sequence: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human NAP-2 / PPBP / CXCL7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human NAP-2 / PPBP / CXCL7 Protein General Information | |
|---|---|
| Alternate Names | |
| NAP-2; PPBP; CXCL7; Cxcl7; NAP-2; TGB1; 2400003M24Rik; CTAP3; LDGF; AI854500; b-TG1; LA-PF4; MDGF; NAP-2-L1; Scyb7; THBGB1; beta-TG; TGB; CTAPIII | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PPBP |
| Entrez Gene ID | 5473 |
| Ensemble Gene ID | ENSG00000163736 |
| RefSeq Protein Accession(s) | NP_002695.1 |
| RefSeq mRNA Accession(s) | NM_002704.3 |
| UniProt ID(s) | P02775 |
| UniGene ID(s) | Hs.2164 |
| HGNC ID(s) | HGNC:9240 |
| COSMIC ID Link(s) | PPBP |
| KEGG Gene ID(s) | hsa:5473 |
| PharmGKB ID(s) | PA33561 |
| General Description of Recombinant Human NAP-2 / PPBP / CXCL7 Protein. | |
| LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are choattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chokine-induced neutrophil activation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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