PDF DatasheetHuman Osteonectin / SPARC Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Osteonectin / SPARC based upon sequence from: Human
Host: QP8664 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Osteonectin / SPARC, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8664.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala18 – Ile303
Amino Acid Sequence: APQQEALPDE TEVVEETVAE VTEVSVGANP VQVEVGEFDD GAEETEEEVV AENPCQNHHC KHGKVCELDE NNTPMCVCQD PTSCPAPIGE FEKVCSNDNK TFDSSCHFFA TKCTLEGTKK GHKLHLDYIG PCKYIPPCLD SELTEFPLRM RDWLKNVLVT LYERDEDNNL LTEKQKLRVK KIHENEKRLE AGDHPVELLA RDFEKNYNMY IFPVHWQFGQ LDQHPIDGYL SHTELAPLRA PLIPMEHCTT RFFETCDLDN DKYIALDEWA GCFGIKQKDI DKDLVI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Osteonectin / SPARC Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Osteonectin / SPARC Protein General Information | |
|---|---|
| Alternate Names | |
| Osteonectin; SPARC; BM-40; ON; OI17 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SPARC |
| Entrez Gene ID | 6678 |
| Ensemble Gene ID | ENSG00000113140 |
| RefSeq Protein Accession(s) | NP_001296372.1 |
| RefSeq mRNA Accession(s) | NM_001309443.1, NM_001309444.1, NM_003118.3 |
| UniProt ID(s) | P09486 |
| UniGene ID(s) | Hs.111779 |
| HGNC ID(s) | HGNC:11219 |
| COSMIC ID Link(s) | SPARC |
| KEGG Gene ID(s) | hsa:6678 |
| PharmGKB ID(s) | PA36055 |
| General Description of Recombinant Human Osteonectin / SPARC Protein. | |
| Appears to regulate cell growth through interactions with the Extracellular domain matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell mbranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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