PDF DatasheetHuman Tenascin C Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tenascin C based upon sequence from: Human
Host: QP8717 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tenascin C, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8717.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp1888 – Ala2201
Amino Acid Sequence: DSPRDLTATE VQSETALLTW RPPRASVTGY LLVYESVDGT VKEVIVGPDT TSYSLADLSP STHYTAKIQA LNGPLRSNMI QTIFTTIGLL YPFPKDCSQA MLNGDTTSGL YTIYLNGDKA EALEVFCDMT SDGGGWIVFL RRKNGRENFY QNWKAYAAGF GDRREEFWLG LDNLNKITAQ GQYELRVDLR DHGETAFAVY DKFSVGDAKT RYKLKVEGYS GTAGDSMAYH NGRSFSTFDK DTDSAITNCA LSYKGAFWYR NCHRVNLMGR YGDNNHSQGV NWFHWKGHEH SIQFAEMKLR PSNFRNLEGR RKRA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Tenascin C Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Tenascin C Protein General Information | |
|---|---|
| Alternate Names | |
| Tenascin C; 150-225; GMEM; JI; GP; TN; TN-C; DFNA56; HXB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNC |
| Entrez Gene ID | 3371 |
| Ensemble Gene ID | ENSG00000041982 |
| RefSeq Protein Accession(s) | NP_002151.2 |
| RefSeq mRNA Accession(s) | NM_002160.3, XM_005251972.3, XM_005251974.3, XM_005251975.3, XM_011518629.2 |
| UniProt ID(s) | P24821 |
| UniGene ID(s) | Hs.143250 |
| HGNC ID(s) | HGNC:5318 |
| COSMIC ID Link(s) | TNC |
| KEGG Gene ID(s) | hsa:3371 |
| PharmGKB ID(s) | PA35103 |
| General Description of Recombinant Human Tenascin C Protein. | |
| Extracellular domain matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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