PDF DatasheetHuman TIMP-3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TIMP-3 based upon sequence from: Human
Host: QP8728 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TIMP-3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8728.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: His30 – Ala208
Amino Acid Sequence: HPQDAFCNSD IVIRAKVVGK KLVKEGPFGT LVYTIKQMKM YRGFTKMPHV QYIHTEASES LCGLKLEVNK YQYLLTGRVY DGKMYTGLCN FVERWDQLTL SQRKGLNYRY HLGCNCKIKS CYYLPCFVTS KNECLWTDML SNFGYPGYQS KHYACIRQKG GYCSWYRGWA PPDKSIINA
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TIMP-3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TIMP-3 Protein General Information | |
|---|---|
| Alternate Names | |
| TIMP-3; K222; HSMRK222; K222TA2; SFD | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TIMP3 |
| Entrez Gene ID | 7078 |
| Ensemble Gene ID | ENSG00000100234 |
| RefSeq Protein Accession(s) | NP_000353.1 |
| RefSeq mRNA Accession(s) | NM_000362.4 |
| UniProt ID(s) | P35625 |
| UniGene ID(s) | Hs.644633 |
| HGNC ID(s) | HGNC:11822 |
| COSMIC ID Link(s) | TIMP3 |
| KEGG Gene ID(s) | hsa:7078 |
| PharmGKB ID(s) | PA36528 |
| General Description of Recombinant Human TIMP-3 Protein. | |
| Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates th by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to rodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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