PDF DatasheetPig C5a / Complement 5a Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant C5a / Complement 5a based upon sequence from: Pig
Host: QP9020 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Sus scrofa (Pig) C5a / Complement 5a, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9020.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Arg74
Amino Acid Sequence: MLQKKIEEEA AKYKYAMLKK CCYDGAYRND DETCEERAAR IKIGPKCVKA FKDCCYIANQ VRAEQSHKNI QLGR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Pig C5a / Complement 5a Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Porcine C5a / Complement 5a Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | C5 |
| UniProt ID(s) | P01032 |
| UniGene ID(s) | Ssc.21108 |
| COSMIC ID Link(s) | C5 |
| General Description of Recombinant Porcine C5a / Complement 5a Protein. | |
| Derived from proteolytic degradation of complent C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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