PDF DatasheetHuman Endothelin-1 receptor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Endothelin-1 receptor based upon sequence from: Human
Host: QP9110 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Endothelin-1 receptor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9110.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Asp21 – Lys80
Amino Acid Sequence: DNPERYSTNL SNHVDDFTTF RGTELSFLVT THQPTNLVLP SNGSMHNYCP QQTKITSAFK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Endothelin-1 receptor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Endothelin-1 receptor Protein General Information | |
|---|---|
| Alternate Names | |
| ETA; ETA-R; ET-A; ETAR; ETRA; MFDA; hET-AR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EDNRA |
| Entrez Gene ID | 1909 |
| Ensemble Gene ID | ENSG00000151617 |
| RefSeq Protein Accession(s) | NP_001159527.1 |
| RefSeq mRNA Accession(s) | NM_001166055.1, NM_001256283.1, NM_001957.3 |
| UniProt ID(s) | P25101 |
| UniGene ID(s) | Hs.183713 |
| HGNC ID(s) | HGNC:3179 |
| COSMIC ID Link(s) | EDNRA |
| KEGG Gene ID(s) | hsa:1909 |
| PharmGKB ID(s) | PA27617 |
| General Description of Recombinant Human Endothelin-1 receptor Protein. | |
| Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger syst. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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