PDF DatasheetHuman Endothelin-1 receptor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Endothelin-1 receptor based upon sequence from Human
Host: QP9952 protein expressed in Invitro-E.coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Endothelin-1 receptor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9952.
Bioactivity Data: Untested
Full Length? Full Length Transmembrane Protein
Expression Region: Met21427
Amino Acid Sequence: MASMTGGQQM GRGSDNPERY STNLSNHVDD FTTFRGTELS FLVTTHQPTN LVLPSNGSMH NYCPQQTKIT SAFKYINTVI SCTIFIVGMV GNATLLRIIY QNKCMRNGHN ALIASLALGD LIYVVIDLPI NVFKLLAGRW PFDHNDFGVF LCKLFPFLQK SSVGITVLNL CALSVDRYRA VASWSRVQGI GIPLVTAIEI VSIWILSFIL AIPEAIGFVM VPFEYRGEQH KTCMLNATSK FMEFYQDVKD WWLFGFYFCM PLVCTAIFYT LMTCEMLNRR NGSLRIALSE HLKQRREVAK TVFCLVVIFA LCWFPVHLSR ILKKTVYNEM DKNRCELLSF LLLMDYIGIN LATMNSCINP IALYFVSKKF KNCFQSCLCC CCYQSKSLMT SVPMNGTSIQ WKDHDQNNHN TDRSSHKDSM N
Purity: Greater than 85% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Endothelin-1 receptor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Endothelin-1 receptor Protein General Information | |
|---|---|
| Alternate Names | |
| ETA; ETA-R; ET-A; ETAR; ETRA; MFDA; hET-AR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | EDNRA |
| Entrez Gene ID | 1909 |
| Ensemble Gene ID | ENSG00000151617 |
| RefSeq Protein Accession(s) | NP_001159527.1 |
| RefSeq mRNA Accession(s) | NM_001166055.1, NM_001256283.1, NM_001957.3 |
| UniProt ID(s) | P25101 |
| UniGene ID(s) | Hs.183713 |
| HGNC ID(s) | HGNC:3179 |
| COSMIC ID Link(s) | EDNRA |
| KEGG Gene ID(s) | hsa:1909 |
| PharmGKB ID(s) | PA27617 |
| General Description of Recombinant Human Endothelin-1 receptor Protein. | |
| Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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