PDF DatasheetMouse IFNAR2 / IFNABR Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IFNAR2 / IFNABR based upon sequence from: Mouse
Host: QP9199 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) IFNAR2 / IFNABR, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9199.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ser22 – Ala242
Amino Acid Sequence: SLETITPSAF DGYPDEPCTI NITIRNSRLI LSWELENKSG PPANYTLWYT VMSKDENLTK VKNCSDTTKS SCDVTDKWLE GMESYVVAIV IVHRGDLTVC RCSDYIVPAN APLEPPEFEI VGFTDHINVT MEFPPVTSKI IQEKMKTTPF VIKEQIGDSV RKKHEPKVNN VTGNFTFVLR DLLPKTNYCV SLYFDDDPAI KSPLKCIVLQ PGQESGLSES A
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IFNAR2 / IFNABR Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse IFNAR2 / IFNABR Protein General Information | |
|---|---|
| Alternate Names | |
| IFNAR2; IFNABR; IFN-R; IFN-alpha-REC; IFNABR; IMD45; IFNARB | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Ifnar2 |
| Entrez Gene ID | 15976 |
| Ensemble Gene ID | ENSMUSG00000022971 |
| RefSeq Protein Accession(s) | NP_001103968.1 |
| RefSeq mRNA Accession(s) | NM_001110498.1, NM_001347258.1, NM_010509.2 |
| UniProt ID(s) | O35664 |
| UniGene ID(s) | Mm.6834 |
| COSMIC ID Link(s) | Ifnar2 |
| KEGG Gene ID(s) | mmu:15976 |
| General Description of Recombinant Mouse IFNAR2 / IFNABR Protein. | |
| Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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