PDF DatasheetHuman MAGE-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MAGE-1 based upon sequence from: Human
Host: QP9261 protein expressed in Mammal, Yeast..
Tag: Flag
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MAGE-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP9261.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Val309
Amino Acid Sequence: MSLEQRSLHC KPEEALEAQQ EALGLVCVQA ATSSSSPLVL GTLEEVPTAG STDPPQSPQG ASAFPTTINF TRQRQPSEGS SSREEEGPST SCILESLFRA VITKKVADLV GFLLLKYRAR EPVTKAEMLE SVIKNYKHCF PEIFGKASES LQLVFGIDVK EADPTGHSYV LVTCLGLSYD GLLGDNQIMP KTGFLIIVLV MIAMEGGHAP EEEIWEELSV MEVYDGREHS AYGEPRKLLT QDLVQEKYLE YRQVPDSDPA RYEFLWGPRA LAETSYVKVL EYVIKVSARV RFFFPSLREA ALREEEEGV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MAGE-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MAGE-1 Protein General Information | |
|---|---|
| Alternate Names | |
| MAGE-1; CT1.1; MAGE1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MAGEA1 |
| Entrez Gene ID | 4100 |
| Ensemble Gene ID | ENSG00000198681 |
| RefSeq Protein Accession(s) | NP_004979.3 |
| RefSeq mRNA Accession(s) | NM_004988.4 |
| UniProt ID(s) | P43355 |
| UniGene ID(s) | Hs.72879 |
| HGNC ID(s) | HGNC:6796 |
| COSMIC ID Link(s) | MAGEA1 |
| KEGG Gene ID(s) | hsa:4100 |
| PharmGKB ID(s) | PA30542 |
| General Description of Recombinant Human MAGE-1 Protein. | |
| May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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