PDF DatasheetMouse Ripk3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ripk3 based upon sequence from Mouse
Host: QP9919 protein expressed in Yeast.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Ripk3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP9919.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys486
Amino Acid Sequence: MSSVKLWPTG ASAVPLVSRE ELKKLEFVGK GGFGVVFRAH HRTWNHDVAV KIVNSKKISW EVKAMVNLRN ENVLLLLGVT EDLQWDFVSG QALVTRFMEN GSLAGLLQPE CPRPWPLLCR LLQEVVLGMC YLHSLDPPLL HRDLKPSNIL LDPELHAKLA DFGLSTFQGG SQSGSGSGSG SRDSGGTLAY LDPELLFKVN LKASKASDVY SFGILVWAVL AGREAELVDK TSLIRETVCD RQSRPPLTEL PPGSPETPGL EKLKELMIHC WGSQSENRPS FQDCEPKTNE VYNLVKDKVD AAVSEVKHYL SQHRSSGRNL SAREPSQRGT EMDCPRETMV SKMLDRLHLE EPSGPVPGKC PERQAQDTSV GPATPARTSS DPVAGTPQIP HTLPFRGTTP GPVFTETPGP HPQRNQGDGR HGTPWYPWTP PNPMTGPPAL VFNNCSEVQI GNYNSLVAPP RTTASSSAKY DQAQFGRGRG WQPFHK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Ripk3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Ripk3 Protein General Information | |
|---|---|
| Alternate Names | |
| Rip3; 2610528K09Rik; AW107945; Receptor-interacting serine/threonine-protein kinase | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Ripk3 |
| Entrez Gene ID | 56532 |
| Ensemble Gene ID | ENSMUSG00000022221 |
| RefSeq Protein Accession(s) | NP_064339.2 |
| RefSeq mRNA Accession(s) | NM_019955.2 |
| UniProt ID(s) | Q9QZL0 |
| UniGene ID(s) | Mm.46612 |
| COSMIC ID Link(s) | Ripk3 |
| KEGG Gene ID(s) | mmu:56532 |
| General Description of Recombinant Mouse Ripk3 Protein. | |
| Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family mbers. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.