PDF DatasheetRat CCL5 / RANTES Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL5 / RANTES based upon sequence from Rat
Host: QP5513 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5513.
Bioactivity Data: THP-1 chemotaxis significantly induced by less than 250 ng/ml of Rat CCL5 / RANTES.
Monomer or Dimer: Monomer
Amino Acid Sequence: SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Rat CCL5 / RANTES Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Rat CCL5 / RANTES Protein General Information | |
|---|---|
| Alternate Names | |
| CCL5, RANTES, SISd, TCP228, D17S136E, RANTES, SCYA5, SIS-delta, eoCP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL5 |
| Entrez Gene ID | 20304 |
| RefSeq Protein Accession(s) | NP_038681.2 |
| RefSeq mRNA Accession(s) | NM_013653.3 |
| UniProt ID(s) | Q5XZF2 |
| UniGene ID(s) | Mm.284248 |
| KEGG Gene ID(s) | mmu:20304 |
| General Description of Recombinant Rat CCL5 / RANTES Protein . | |
| Regulated upon activation, normal T cell expressed and secreted (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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