Human Anti-CFTR Antibody Product Attributes
Tested Applications: Immunohistochemistry (IHC).
Anti-CFTR Antibody Clone: CFTR/1785
Clone CFTR/1785 Host and Isotype: Mouse IgG2b
Anti-Human CFTR Positive Control Sample: MOLT-4 cells. Pancreas, Kidney or Placenta.
Cellular Localization of Antibody
Cell Surface and Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human CFTR fragment (aa258-385)
Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.
CFTR Previously Observed Antibody Staining Patterns
Observed Antibody Staining Data By Tissue Type:Variations in CFTR antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of CFTR could be seen inglandular cells in the salivary gland. We were unable to detect CFTR in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
Observed Antibody Staining Data By Tissue Disease Status:Tissues from cancer patients, for instance, have their own distinct pattern of CFTR expression as measured by anti-CFTR antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.
|Sample Type||breast cancer||carcinoid||cervical cancer||colorectal cancer||endometrial cancer||glioma||head and neck cancer||liver cancer||lung cancer||lymphoma||melanoma||ovarian cancer||pancreatic cancer||prostate cancer||renal cancer||skin cancer||stomach cancer||testicular cancer||thyroid cancer||urothelial cancer|
Limitations and Warranty
enQuire Bio's CFTR Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.