Western Blot Analysis of Recombinant Protein and HeLa Cell Lysate using Factor XIIIa Monoclonal Antibody (F13A1/1448).
Western Blot Analysis of Recombinant Protein and HeLa Cell Lysate using Factor XIIIa Monoclonal Antibody (F13A1/1448).

Anti-Factor XIIIa Antibody Clone F13A1/1448

$ 118.00$ 418.00
Please Select Product Options Below To View The Catalog Number.

SKU: 2162-MSM2
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b kappa
Mass Spec Validated?: Not MS Validated

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Datasheets and Documentation
Product Datasheet
SKU: 2162-MSM2-P0
Factor XIIIa General Information
Alternate Names
Coagulation factor XIII A chain, F13A1
Molecular Weight
83kDa
Chromosomal Location
6p25.3-p24.3
Curated Database and Bioinformatic Data
Gene SymbolF13A1
Entrez Gene ID2162
Ensemble Gene IDENSG00000124491
RefSeq Protein Accession(s)NP_000120
RefSeq mRNA Accession(s)NM_000129
RefSeq Genomic Accession(s)NC_018917, NC_000006, NG_008107
UniProt ID(s)P00488
UniGene ID(s)P00488
HGNC ID(s)3531
Cosmic ID(s)F13A1
KEGG Gene ID(s)hsa:2162
PharmGKB ID(s)PA162
General Description of Factor XIIIa.
This MAb recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.

Human Anti-Factor XIIIa Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-Factor XIIIa Antibody Clone: F13A1/1448
Clone F13A1/1448 Host and Isotype: Mouse IgG2b kappa
Anti-Human Factor XIIIa Positive Control Sample: 293T Cells. Placenta.
Cellular Localization of Antibody Cytoplasmic and Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant fragment of human Factor XIIIa protein (aa46-181)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

Factor XIIIa Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in Factor XIIIa antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in fibroblasts in mesenchymal tissue. More moderate antibody staining intensity was present in fibroblasts in mesenchymal tissue. Low, but measureable presence of Factor XIIIa could be seen inadipocytes in mesenchymal tissue and Leydig cells in the testis. We were unable to detect Factor XIIIa in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's Factor XIIIa Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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