SDS–PAGE Analysis Purified Ubiquitin Mouse Monoclonal Antibody (UBB/2122).Confirmation of purity and integrity.
SDS–PAGE Analysis Purified Ubiquitin Mouse Monoclonal Antibody (UBB/2122).Confirmation of purity and integrity.Analysis of Protein Array containing more than 19,000 full-length human proteins using Ubiquitin Mouse Monoclonal Antibody (UBB/2122)Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.  A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.Formalin-fixed, paraffin-embedded human Brain stained with Ubiquitin Mouse Monoclonal Antibody (UBB/2122).

Ubiquitin (Autophagy Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 158.00$ 348.00
Please Select Product Options Below To View The Catalog Number.

SKU: 7314-MSM2
Species: Human
Tested Applications: IHC, ELISA
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

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Shipping Information
In Stock: 1-2 Day Lead Time.
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Datasheets and Documentation
Product Datasheet
SKU: 7314-MSM2-P0
Ubiquitin (Autophagy Marker) General Information
Alternate Names
Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; Ubiquitin; Ubiquitin B
Molecular Weight
9kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol7314
Entrez Gene IDUBB
UniProt ID(s)P0CG47; P0CG48; P62979; P62987 and P62988
UniGene ID(s)Hs356190 and 520348
COSMIC ID Link(s)UBB
KEGG Gene ID(s)hsa:7314
General Description of Ubiquitin (Autophagy Marker).
Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.

Human Anti-Ubiquitin (Autophagy Marker) Antibody Product Attributes

Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-Ubiquitin (Autophagy Marker) Antibody Clone: UBB/2122
Clone UBB/2122 Host and Isotype: Mouse IgG1, kappa
Anti-Human Ubiquitin (Autophagy Marker) Positive Control Sample: HeLa or Jurkat cells. Alzheimer s Brain
Cellular Localization of Antibody UBB/2122 Staining: Cell Surface, Cytoplasmic and Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human Ubiquitin protein (apprx. aa 1-119) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Ubiquitin (Autophagy Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, Ubiquitin (Autophagy Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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Ubiquitin (Autophagy Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

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