Recombinant Human IL-1 beta / IL1B Protein

$ 98.00$ 2,398.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10307
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 153

Product NumberDescriptionPrice
QP10307-ec-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 108.00
QP10307-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 278.00
QP10307-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,488.00
QP10307-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 2,688.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10307-ec-2ug
Recombinant Human IL-1 beta / IL1B Protein General Information
Alternate Names
IL-1 beta; IL1B; IL-1; IL1-BETA; IL1F2
Curated Database and Bioinformatic Data
Gene SymbolIL1B
Entrez Gene ID3553
Ensemble Gene IDENSG00000125538
RefSeq Protein Accession(s)NP_000567.1
RefSeq mRNA Accession(s)NM_000576.2
UniProt ID(s)P01584
UniGene ID(s)Hs.126256
HGNC ID(s)HGNC:5992
COSMIC ID Link(s)IL1B
KEGG Gene ID(s)hsa:3553
PharmGKB ID(s)PA29808
General Description of Recombinant Human IL-1 beta / IL1B Protein.
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Human IL-1 beta / IL1B Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-1 beta / IL1B based upon sequence from: Human
Host: QP10307 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL-1 beta / IL1B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10307.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg/ml, corresponding to a specific activity of > 1.0 × 109 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL-1 beta / IL1B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL-1 beta / IL1B Protein