Recombinant Human IL-1RA / IL1RN Protein

$ 98.00$ 528.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10308
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 152

Product NumberDescriptionPrice
QP10308-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 98.00
QP10308-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 248.00
QP10308-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 528.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10308-ec-20ug
Recombinant Human IL-1RA / IL1RN Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolIL1RN
Entrez Gene ID3557
Ensemble Gene IDENSG00000136689
RefSeq Protein Accession(s)NP_000568.1
RefSeq mRNA Accession(s)NM_000577.4, NM_001318914.1, NM_173841.2, NM_173842.2, NM_173843.2, XM_005263661.4, XM_011511121.1
UniProt ID(s)P18510
UniGene ID(s)Hs.81134
HGNC ID(s)HGNC:6000
COSMIC ID Link(s)IL1RN
KEGG Gene ID(s)hsa:3557
PharmGKB ID(s)PA29816
General Description of Recombinant Human IL-1RA / IL1RN Protein.
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.

Human IL-1RA / IL1RN Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-1RA / IL1RN based upon sequence from: Human
Host: QP10308 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL-1RA / IL1RN, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10308.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by inhibiting IL-1alpha- dependent proliferation of murine D10S cells is less than 40 ng/ml, corresponding to a specific activity of > 2.5 × 104 IU/mg in the presence of 50 pg/ml rHuIL-1alpha.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: RPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSE NRKQDKRFAF IRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDEG VMVTKFYFQE DE
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL-1RA / IL1RN Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL-1RA / IL1RN Protein