Recombinant Human IL6 / Interleukin-6 Protein

$ 98.00$ 1,838.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10313
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 186

Product NumberDescriptionPrice
QP10313-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
QP10313-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 248.00
QP10313-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,018.00
QP10313-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,838.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10313-ec-5ug
Recombinant Human IL6 / Interleukin-6 Protein Protein General Information
Alternate Names
IL6; Interleukin-6 Protein; BSF2; IL-6; HSF; BSF-2; CDF; HGF; IFN-beta-2; IFNB2
Curated Database and Bioinformatic Data
Gene SymbolIL6
Entrez Gene ID3569
Ensemble Gene IDENSG00000136244
RefSeq Protein Accession(s)NP_000591.1
RefSeq mRNA Accession(s)NM_000600.4, XM_011515390.2
UniProt ID(s)P05231
UniGene ID(s)Hs.654458
HGNC ID(s)HGNC:6018
COSMIC ID Link(s)IL6
KEGG Gene ID(s)hsa:3569
PharmGKB ID(s)PA198
General Description of Recombinant Human IL6 / Interleukin-6 Protein Protein.
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

Human IL6 / Interleukin-6 Protein Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL6 / Interleukin-6 Protein based upon sequence from: Human
Host: QP10313 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL6 / Interleukin-6 Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10313.
Bioactivity Data: Assay #1: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0 × 107 IU/mg. Assay #2: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine T1165 cells is less than 0.8 ng/ml, corresponding to a specific activity of > 1.25 ×106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENN LNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK V LIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR AL RQM
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL6 / Interleukin-6 Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4. , lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL6 / Interleukin-6 Protein

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