Recombinant Human Interleukin-21 / IL-21 Protein

$ 108.00$ 3,578.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10326
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 133

Product NumberDescriptionPrice
QP10326-ec-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 98.00
QP10326-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 248.00
QP10326-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,778.00
QP10326-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 3,188.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10326-ec-2ug
Recombinant Human Interleukin-21 / IL-21 Protein Protein General Information
Alternate Names
Interleukin-21; IL-21 Protein; CVID11; IL-21; Za11
Curated Database and Bioinformatic Data
Gene SymbolIL21
Entrez Gene ID59067
Ensemble Gene IDENSG00000138684
RefSeq Protein Accession(s)NP_001193935.1
RefSeq mRNA Accession(s)NM_001207006.2, NM_021803.3
UniProt ID(s)Q9HBE4
UniGene ID(s)Hs.567559
HGNC ID(s)HGNC:6005
COSMIC ID Link(s)IL21
KEGG Gene ID(s)hsa:59067
PharmGKB ID(s)PA29820
General Description of Recombinant Human Interleukin-21 / IL-21 Protein Protein.
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Human Interleukin-21 / IL-21 Protein Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Interleukin-21 / IL-21 Protein based upon sequence from: Human
Host: QP10326 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Interleukin-21 / IL-21 Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10326.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by by a cell proliferation assay using human N1186 T cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QGQDRHMIRM RQLIDIVDQL KNYVNDLVPE FLPAPEDVET NCEWSAFSCF QKAQLKSANT GNNERIINVS IKKLKRKPPS TNAGRRQKHR LTCPSCDSYE KKPPKEFLER FKSLLQKMIH QHLSSRTHGS EDS
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Interleukin-21 / IL-21 Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Interleukin-21 / IL-21 Protein