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Recombinant Human M-CSF / CSF-1 Protein

$ 98.00$ 2,638.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10351
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 158

Product NumberDescriptionPrice
QP10351-ec-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 98.00
QP10351-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 248.00
QP10351-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,468.00
QP10351-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 2,638.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10351-ec-2ug
Recombinant Human M-CSF / CSF-1 Protein General Information
Alternate Names
M-CSF; CSF-1; C87615; MCSF; Csfm
Curated Database and Bioinformatic Data
Gene SymbolCSF1
Entrez Gene ID1435
Ensemble Gene IDENSG00000184371
RefSeq Protein Accession(s)NP_000748.3
RefSeq mRNA Accession(s)NM_000757.5, NM_172210.2, NM_172211.3, NM_172212.2
UniProt ID(s)P09603
UniGene ID(s)Hs.173894
HGNC ID(s)HGNC:2432
COSMIC ID Link(s)CSF1
KEGG Gene ID(s)hsa:1435
PharmGKB ID(s)PA26935
General Description of Recombinant Human M-CSF / CSF-1 Protein.
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

Human M-CSF / CSF-1 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant M-CSF / CSF-1 based upon sequence from: Human
Host: QP10351 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human M-CSF / CSF-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10351.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine M-NFS-60 cells is less than 1 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: EEVSEYCSHM IGSGHLQSLQ RLIDSQMETS CQITFEFVDQ EQLKDPVCYL KKAFLLVQDI MEDTMRFRDN TPNAIAIVQL QELSLRLKSC FTKDYEEHDK ACVRTFYETP LQLLEKVKNV FNETKNLLDK DWNIFSKNCN NSFAECSSQG HERQSEGS
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human M-CSF / CSF-1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0. 2um filtered PBS, pH7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human M-CSF / CSF-1 Protein