Recombinant Human CD40L / CD154 / TNFSF5 Protein

$ 108.00$ 1,028.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10359
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 149

Product NumberDescriptionPrice
QP10359-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 108.00
QP10359-ec-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 278.00
QP10359-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 568.00
QP10359-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,028.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10359-ec-10ug
Recombinant Human CD40L / CD154 / TNFSF5 Protein General Information
Alternate Names
CD40L; CD154; TNFSF5; CD154; IGM; Ly-62; TRAP; Tnlg8b; HIGM1; CD40-L; Cd40l; Ly62; T-BAM; IMD3; Tnfsf5; gp39
Curated Database and Bioinformatic Data
Gene SymbolCD40LG
Entrez Gene ID959
Ensemble Gene IDENSG00000102245
RefSeq Protein Accession(s)NP_000065.1
RefSeq mRNA Accession(s)NM_000074.2
UniProt ID(s)P29965
UniGene ID(s)Hs.592244
HGNC ID(s)HGNC:11935
COSMIC ID Link(s)CD40LG
KEGG Gene ID(s)hsa:959
PharmGKB ID(s)PA36626
General Description of Recombinant Human CD40L / CD154 / TNFSF5 Protein.
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. ; Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

Human CD40L / CD154 / TNFSF5 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant CD40L / CD154 / TNFSF5 based upon sequence from: Human
Host: QP10359 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CD40L / CD154 / TNFSF5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10359.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CD40L / CD154 / TNFSF5 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.0, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CD40L / CD154 / TNFSF5 Protein