Recombinant Human Fibroblast growth factor 19 Protein

$ 98.00$ 1,428.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10383
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 195

Product NumberDescriptionPrice
QP10383-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
QP10383-ec-25ug Size: 25 ug, Tag: Untagged (Native Protein) $ 248.00
QP10383-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 818.00
QP10383-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,428.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10383-ec-5ug
Recombinant Human Fibroblast growth factor 19 Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolFGF19
Entrez Gene ID9965
Ensemble Gene IDENSG00000162344
RefSeq Protein Accession(s)NP_005108.1
RefSeq mRNA Accession(s)NM_005117.2
UniProt ID(s)O95750
UniGene ID(s)Hs.249200
HGNC ID(s)HGNC:3675
COSMIC ID Link(s)FGF19
KEGG Gene ID(s)hsa:9965
PharmGKB ID(s)PA28114
General Description of Recombinant Human Fibroblast growth factor 19 Protein.
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.

Human Fibroblast growth factor 19 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Fibroblast growth factor 19 based upon sequence from: Human
Host: QP10383 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Fibroblast growth factor 19, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10383.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 150 ng/ml, corresponding to a specific activity of > 6.7 × 103 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Fibroblast growth factor 19 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Fibroblast growth factor 19 Protein