Recombinant Human Thrombopoietin / THPO Protein

$ 98.00 – $ 1,838.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10387
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 252

Product Number	Description	Price
QP10387-ec-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 108.00
QP10387-ec-25ug	Size: 25 ug, Tag: Untagged (Native Protein)	$ 278.00
QP10387-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,148.00
QP10387-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 2,058.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10387-ec-5ug

Recombinant Human Thrombopoietin / THPO Protein General Information
Alternate Names
Thrombopoietin; THPO; Ml; Mpllg; Mgdf; Tpo
Curated Database and Bioinformatic Data
Gene Symbol	IGFBP5
Entrez Gene ID	3488
Ensemble Gene ID	ENSG00000115461
RefSeq Protein Accession(s)	NP_000590.1
RefSeq mRNA Accession(s)	NM_000599.3
UniProt ID(s)	P24593
HGNC ID(s)	HGNC:5474
COSMIC ID Link(s)	IGFBP5
KEGG Gene ID(s)	hsa:3488
PharmGKB ID(s)	PA29707
General Description of Recombinant Human Thrombopoietin / THPO Protein.
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Human Thrombopoietin / THPO Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Thrombopoietin / THPO based upon sequence from: Human

Host: QP10387 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human Thrombopoietin / THPO, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10387.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 ug/ml, corresponding to a specific activity of > 2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: LGSFVHCEPC DEKALSMCPP SPLGCELVKE PGCGCCMTCA LAEGQSCGVY TERCAQGLRC LPRQDEEKPL HALLHGRGVC LNEKSYREQV KIERDSREHE EPTTSEMAEE TYSPKIFRPK HTRISELKAE AVKKDRRKKL TQSKFVGGAE NTAHPRIISA PEMRQESEQG PCRRHMEASL QELKASPRMV PRAVYLPNCD RKGFYKRKQC KPSRGRKRGI CWCVDKYGMK LPGMEYVDGD FQCHTFDSSN VE

Purity: Greater than 96% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human Thrombopoietin / THPO Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.0, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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