Recombinant Human HBEGF / DTR Protein

$ 98.00$ 918.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10400
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 86

Product NumberDescriptionPrice
QP10400-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 98.00
QP10400-ec-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 248.00
QP10400-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 508.00
QP10400-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 918.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10400-ec-10ug
Recombinant Human HBEGF / DTR Protein Protein General Information
Alternate Names
HBEGF; DTR Protein; HEGFL; DTSF; DTR; DTS
Curated Database and Bioinformatic Data
Gene SymbolHBEGF
Entrez Gene ID1839
Ensemble Gene IDENSG00000113070
RefSeq Protein Accession(s)NP_001936.1
RefSeq mRNA Accession(s)NM_001945.2
UniProt ID(s)Q99075
UniGene ID(s)Hs.592942
HGNC ID(s)HGNC:3059
COSMIC ID Link(s)HBEGF
KEGG Gene ID(s)hsa:1839
PharmGKB ID(s)PA27513
General Description of Recombinant Human HBEGF / DTR Protein Protein.
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Human HBEGF / DTR Protein Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant HBEGF / DTR Protein based upon sequence from: Human
Host: QP10400 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human HBEGF / DTR Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10400.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: DLQEADLDLL RVTLSSKPQA LATPNKEEHG KRKKKGKGLG KKRDPCLRKY KDFCIHGECK YVKELRAPSC ICHPGYHGER CHGLSL
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human HBEGF / DTR Protein Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 130 mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human HBEGF / DTR Protein

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