Recombinant Human Protein CYR61 Protein

$ 98.00$ 1,858.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10401
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 357

Product NumberDescriptionPrice
QP10401-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
QP10401-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 248.00
QP10401-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,058.00
QP10401-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,858.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10401-ec-5ug
Recombinant Human Protein CYR61 Protein General Information
Alternate Names
CCN1; IGFBP10; GIG1
Curated Database and Bioinformatic Data
Gene SymbolCYR61
Entrez Gene ID3491
Ensemble Gene IDENSG00000142871
RefSeq Protein Accession(s)NP_001545.2
RefSeq mRNA Accession(s)NM_001554.4
UniProt ID(s)O00622
UniGene ID(s)Hs.8867
HGNC ID(s)HGNC:2654
COSMIC ID Link(s)CYR61
KEGG Gene ID(s)hsa:3491
PharmGKB ID(s)PA27126
General Description of Recombinant Human Protein CYR61 Protein.
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Human Protein CYR61 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant Protein CYR61 based upon sequence from: Human
Host: QP10401 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Protein CYR61, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10401.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/3T3 cells is less than 3.0 ug/ml, corresponding to a specific activity of > 330 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: TCPAACHCPL EAPKCAPGVG LVRDGCGCCK VCAKQLNEDC SKTQPCDHTK GLECNFGASS TALKGICRAQ SEGRPCEYNS RIYQNGESFQ PNCKHQCTCI DGAVGCIPLC PQELSLPNLG CPNPRLVKVT GQCCEEWVCD EDSIKDPMED QDGLLGKELG FDASEVELTR NNELIAVGKG SSLKRLPVFG MEPRILYNPL QGQKCIVQTT SWSQCSKTCG TGISTRVTND NPECRLVKET RICEVRPCGQ PVYSSLKKGK KCSKTKKSPE PVRFTYAGCL SVKKYRPKYC GSCVDGRCCT PQLTRTVKMR FRCEDGETFS KNVMMIQSCK CNYNCPHANE AAFPFYRLFN DIHKFRD
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Protein CYR61 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered citrate buffer solution, 300 mM NaCl, pH 3.0, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Protein CYR61 Protein

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