Recombinant Human IL-29 / Interleukin-29 Protein

$ 98.00$ 1,838.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10410
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 181

Product NumberDescriptionPrice
QP10410-ec-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 98.00
QP10410-ec-20ug Size: 20 ug, Tag: Untagged (Native Protein) $ 248.00
QP10410-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,018.00
QP10410-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 1,838.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10410-ec-5ug
Recombinant Human IL-29 / Interleukin-29 Protein General Information
Alternate Names
IL-29; Interleukin-29; IL-29; IL29
Curated Database and Bioinformatic Data
Gene SymbolIFNL1
Entrez Gene ID282618
Ensemble Gene IDENSG00000182393
RefSeq Protein Accession(s)NP_742152.1
RefSeq mRNA Accession(s)NM_172140.1
UniProt ID(s)Q8IU54
UniGene ID(s)Hs.406745
HGNC ID(s)HGNC:18363
KEGG Gene ID(s)hsa:282618
PharmGKB ID(s)PA134899000
General Description of Recombinant Human IL-29 / Interleukin-29 Protein.
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Human IL-29 / Interleukin-29 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-29 / Interleukin-29 based upon sequence from: Human
Host: QP10410 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL-29 / Interleukin-29, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10410.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 5 ng/ml, corresponding to a specific activity of > 2.0 × 105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: GPVPTSKPTT TGKGCHIGRF KSLSPQELAS FKKARDALEE SLKLKNWSCS SPVFPGNWDL RLLQVRERPV ALEAELALTL KVLEAAAGPA LEDVLDQPLH TLHHILSQLQ ACIQPQPTAG PRPRGRLHHW LHRLQEAPKK ESAGCLEASV TFNLFRLLTR DLKYVADGNL CLRTSTHPES T
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL-29 / Interleukin-29 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL-29 / Interleukin-29 Protein

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