Recombinant Mouse IL1F5 / IL36RN Protein

$ 98.00$ 3,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10438
Species: Mouse
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 154

Product NumberDescriptionPrice
QP10438-ec-2ug Size: 2 ug, Tag: Untagged (Native Protein) $ 98.00
QP10438-ec-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 248.00
QP10438-ec-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 1,228.00
QP10438-ec-250ug Size: 250 ug, Tag: Untagged (Native Protein) $ 3,678.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10438-ec-2ug
Recombinant Mouse IL1F5 / IL36RN Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolIL36RN
Entrez Gene ID54450
Ensemble Gene IDENSMUSG00000026983
RefSeq Protein Accession(s)NP_001139559.1
RefSeq mRNA Accession(s)NM_001146087.1, NM_001146088.1, NM_019451.2
UniProt ID(s)Q9QYY1
COSMIC ID Link(s)IL36RN
KEGG Gene ID(s)mmu:54450
General Description of Recombinant Mouse IL1F5 / IL36RN Protein.
Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Mouse IL1F5 / IL36RN Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL1F5 / IL36RN based upon sequence from: Mouse
Host: QP10438 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Mouse IL1F5 / IL36RN, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10438.
Bioactivity Data: Measured by its ability to inhibit IL-36gamma induced IL-6 production by human PBMCs.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Mouse IL1F5 / IL36RN Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse IL1F5 / IL36RN Protein