Recombinant Human TNF-alpha Protein

$ 79.00$ 1,418.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5242
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 158

Product NumberDescriptionPrice
QP5242-100ug Size: 100 ug, Tag: Untagged (Native Protein) $ 329.00
QP5242-10ug Size: 10 ug, Tag: Untagged (Native Protein) $ 79.00
QP5242-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 189.00
QP5242-500ug Size: 500 ug, Tag: Untagged (Native Protein) $ 839.00
QP5242-1mg Size: 1 mg, Tag: Untagged (Native Protein) $ 1,418.00
Shipping Information
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP5242-10ug
Recombinant Human TNF-alpha Protein General Information
Alternate Names
TNF-alpha, Tnfa, Tnfsf1a, Tnlg1f, TNF-a, DIF, TNF-alpha, TNFalpha, TNFSF2
Curated Database and Bioinformatic Data
Gene SymbolTNF
Entrez Gene ID7124
Ensemble Gene IDENSG00000204490
RefSeq Protein Accession(s)NP_000585.2
RefSeq mRNA Accession(s)NM_000594.3
UniProt ID(s)P01375
UniGene ID(s)Hs.241570
HGNC ID(s)HGNC:11892
COSMIC ID Link(s)TNF
KEGG Gene ID(s)hsa:7124
PharmGKB ID(s)PA435
General Description of Recombinant Human TNF-alpha Protein.
Tumor necrosis factor alpha (TNFa) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNFa signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNFa functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

Human TNF-alpha Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant TNF-alpha based upon sequence from: Human
Host: E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5242.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2 ng/mL in the Cytolysis of mouse L929 cells in the presence of Actinomycin D assay. The bioactivity acceptance criteria is set at 5 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TNF-alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human TNF-alpha Protein

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